cytogenetic study of 224 bone marrow samples of suspected chronic myelogeneous leukaemia patients

نویسندگان

رکسانا کریمی نژاد

roxana kariminejad مریم زنگنه

maryam zanganeh فرناز عظیمی

farnaz azimi امیر حسین طارم چی

amirhossein taromchi هاله میری

چکیده

with the present specifications for clasification, 95% of chronic myelogeneous leukaemia (cml) cases have the t(9;22), which brings the abl oncogene to the bcr region and results in a hybrid gene bcr/abl. there may be involvement of other chromosomes in 2-10%, and secondry or additional chromosome abberations may present in 60-80% during the progression of the disease. in the majority of the remaining philadelphia negative cmls, the bcr/abl fusion gene transcript can be detected by molecular techniques,...

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عنوان ژورنال:
genetics in the 3rd millennium

جلد ۱، شماره ۳، صفحات ۱۶۶-۱۷۳

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