cytogenetic study of 224 bone marrow samples of suspected chronic myelogeneous leukaemia patients
نویسندگان
چکیده
with the present specifications for clasification, 95% of chronic myelogeneous leukaemia (cml) cases have the t(9;22), which brings the abl oncogene to the bcr region and results in a hybrid gene bcr/abl. there may be involvement of other chromosomes in 2-10%, and secondry or additional chromosome abberations may present in 60-80% during the progression of the disease. in the majority of the remaining philadelphia negative cmls, the bcr/abl fusion gene transcript can be detected by molecular techniques,...
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عنوان ژورنال:
genetics in the 3rd millenniumجلد ۱، شماره ۳، صفحات ۱۶۶-۱۷۳
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